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Table of contents :
Front Cover......Page 1
Preface......Page 6
Contents......Page 8
1. Introduction and Overview......Page 18
2. Toxicogenomics: Gene Expression Analysis and Computational Tools......Page 22
3. Proteomics......Page 42
4. The Potential of Metabonomics in Toxicology......Page 64
5. Quantitative Structure–Toxicity Relationships Using Chemodescriptors and Biodescriptors......Page 78
6. Hormesis: A Key Concept in Toxicology......Page 100
7. Chemical Risk Assessment......Page 110
8. Toxicokinetics: Fundamentals and Applications in Drug Development and Safety Assessment......Page 134
9. Validation of In Vitro Methods for Toxicology Studies......Page 178
10. Chemical Mixtures Risk Assessment and Technological Advances......Page 194
11. Risk-Based Approach to Foods Derived from Genetically Engineered Animals......Page 222
12. Toxicology of Nanomaterials......Page 234
13. The Biological Basis of Experimental Toxicity of Jet Propulsion Fuel–8......Page 252
14. Drug Safety Toxicology......Page 266
15. Statins and Toxicity......Page 290
16. Inhalation Toxicology......Page 314
17. Modern Gas Chromatography–Mass Spectrometry in Human Forensic Toxicology......Page 382
Index......Page 404